Hugh Pickens writes writes "The Atlantic reports that experts in genetics and microbiology are convinced we may be only a few years away from the development of advanced, genetic bio-weapons able to target a single human being based on their DNA. The authors paint a scenario of the development of a virus that causes only mild flu in the general population but when the virus crosses paths with cells containing a very specific DNA sequence, the sequence would act as a molecular key to unlock secondary functions that would trigger a fast-acting neuro-destructive disease that produces memory loss and, eventually, death. The requisite equipment including gene sequencers, micro-array scanners, and mass spectrometers now cost over $1 million but on eBay, it can be had for as little as $10,000. According to Ronald Kessler, the author of the 2009 book In the President's Secret Service, Navy stewards gather bedsheets, drinking glasses, and other objects the president has touched—they are later sanitized or destroyed—in an effort to keep would-be malefactors from obtaining his genetic material. However no amount of Secret Service vigilance can ever fully secure the president's DNA, because an entire genetic blueprint can now be produced from the information within just a single cell. How to protect the President? The authors propose open-sourcing the president's genetic information to a select group of security-cleared researchers who could follow in the footsteps of the computer sciences, where 'red-team exercises,' are extremely common practices so a similar testing environment could be developed for biological war games. 'Advances in biotechnology are radically changing the scientific landscape. We are entering a world where imagination is the only brake on biology,' write the authors. 'In light of this coming synbio revolution, a wider-ranging relationship between scientists and security organizations—one defined by open exchange, continual collaboration, and crowd-sourced defenses—may prove the only way to protect the president.'"

sciencehabit writes "A tonic of gut microbes may be the secret recipe for treating a common hospital scourge. Researchers have pinpointed the exact mix of microbes required to cure mice of chronic infection by Clostridium difficile. The hard-to-treat bacterium infects alomst 336,000 in the US each year and causes bloating, pain, & diarrhea. A similar bacterial cocktail may be able to replace the current controversial treatment involving the intake of a healthy person's fecal matter to restore the right balance of microbes in the gut."

Tator Tot writes "Grape pomace, the mashed up skins and stems left over from making wine and grape juice, could serve as a good starting point for ethanol production, according to a new study (from the Journal of Agriculture and Food Chemistry). Due to growing interest in biofuels, researchers have started looking for cheap and environmentally sustainable ways to produce such fuels, especially ethanol. Biological engineer Jean VanderGheynst at the University of California, Davis, turned to grape pomace, because winemakers in California alone produce over 100,000 tons of the fruit scraps each year, with much of it going to waste."

An anonymous reader writes in a story about a neat potential use for spider silk. "Many people have heard that spider silk is a sort of supermaterial: stronger than steel, tougher than Kevlar, and yet incredibly malleable and flexible. But the silk has other properties that make it ideal for use in electronic devices. Light can travel through a silk strand as easily as it does through a fiber optic cable. 'When we first tested spider silk, we didn’t know what to expect,' said physicist Nolwenn Huby of the Institut de Physique de Rennes in France. 'We thought, "Why not try this as an optical fiber to propagate light?'" Huby and her team were able to transmit laser light down a short strand of the silk on an integrated circuit chip. The silk worked much like glass fiber optic cables, meaning it could carry information for electronic devices, though it had about four orders of magnitude more loss than the glass. Huby said that with a coating and further development, the silk could one day have better transmission capabilities. She will present her results at this year’s Frontiers in Optics conference, Oct. 14 to 18 in Rochester, New York.

Sam Bagot and Will Bratton operate Horto Domi (hortodomi.com), an agricultural project they describe as "beyond organic." They're working with small prefab greenhouses, adding sensors and Arduino-actuated controls, and even including an earthworm breeding area in most domes, because earthworms are good for the soil and can increase plant production. If you're the kind of person whose plants always seem to shrivel up and die, this may be a great way to garden. With watering and other functions automated, it looks like all you have to do is set your controls, plant what you want to grow, and wait for the "time to harvest" alarm to go off. Okay, it might not be that simple, but Sam and Will say their gardening method saves a lot of energy and time. It also looks like fun, besides being an easy way to grow your own 100% organic fruits and vegetables.

another random user writes with this quote from Nature News: "Few researchers have given credence to claims that samples of dinosaur DNA have survived to the present day, but no one knew just how long it would take for genetic material to fall apart. Now, a study of fossils found in New Zealand is laying the matter to rest — and putting paid to hopes of cloning a Tyrannosaurus rex (abstract). After cell death, enzymes start to break down the bonds between the nucleotides that form the backbone of DNA, and micro-organisms speed the decay. In the long run, however, reactions with water are thought to be responsible for most bond degradation. Groundwater is almost ubiquitous, so DNA in buried bone samples should, in theory, degrade at a set rate. Determining that rate has been difficult because it is rare to find large sets of DNA-containing fossils with which to make meaningful comparisons. To make matters worse, variable environmental conditions such as temperature, degree of microbial attack and oxygenation alter the speed of the decay process. By comparing the specimens' ages and degrees of DNA degradation, the researchers calculated that DNA has a half-life of 521 years. That means that after 521 years, half of the bonds between nucleotides in the backbone of a sample would have broken; after another 521 years half of the remaining bonds would have gone; and so on."

tomhath writes with this exerpt from a Reuters story: "The U.S. Supreme Court agreed Friday to hear an Indiana farmer's appeal that challenges the scope of Monsanto Co.'s patent rights on its Roundup Ready seeds. Mr. Bowman bought and planted 'commodity seeds' from a grain elevator. Those soybean seeds were a mix and included some that contained Monsanto's technology. The Supreme Court agreed to hear the case over the objections of the Obama administration, which had urged the justices to leave the lower court rulings in place."

ananyo writes "Japanese researchers have coaxed mouse stem cells into becoming viable eggs that produce healthy offspring. Last year, the same team successfully used mouse stem cells to make functional sperm (other groups have produced sperm cells in vitro). The researchers used a cocktail of growth factors to transform stem cells into egg precursors. When they added these egg precursor cells to embryonic ovary tissue that did not contain sex cells, the mixture spontaneously formed ovary-like structures, which they then grafted onto natural ovaries in female mice. After four weeks, the stem-cell-derived cells had matured into oocytes. The team removed the oocytes from the ovaries, fertilized them and transplanted the embryos into foster mothers. The offspring that were produced grew up to be fertile themselves."

Shipud writes "Bioinformatics science which deals with the study of methods for storing, retrieving, and analyzing molecular biology data. Byte Size Biology writes about ROSALIND, a cool concept in learning bioinformatics, similar to Project Euler. You are given problems of increasing difficulty to solve. Start with nucleotide counting (trivial) and end with genome assembly (putting it mildly, not so trivial). To solve a problem, you download a sample data set, write your code and debug it. Once you think you are ready, you have a time limit to solve and provide an answer for the actual problem dataset. If you mess up, there is a timed new dataset to download. This thing is coder-addictive. Currently in Beta, but a lot of fun and seems stable."

Zothecula writes "The internet has revolutionized global communications and now researchers at Stanford University are looking to provide a similar boost to bioengineering with a new process dubbed "Bi-Fi." The technology uses an innocuous virus called M13 to increase the complexity and amount of information that can be sent from cell to cell. The researchers say the Bi-Fi could help bio-engineers create complex, multicellular communities that work together to carry out important biological functions."

An anonymous reader writes "In 2008, Sherrie Walters, now 42 years old, discovered that she had rapidly spreading basal cell cancer in her ear. The disease is a type of skin cancer. The doctors pursued an aggressive treatment to combat the destructive disease, removing her ear, part of her skull, and her left ear canal. Though Walters was left without an ear, she was still able to hear with the help of a special hearing aid. A few months ago, doctors from the renowned Johns Hopkins University in Baltimore decided to try a new procedure on Walters. Using cartilage from her rib, the doctors stitched a new ear to match her right one. Then their creation was implanted under the skin of her forearm, where the ear grew for months. ...Doctors attached the ear and blood vessels surgically. Another surgery, conducted this week, gave the ear shape and detail. Dr. Patrick Byrne, a revered plastic and reconstructive surgeon, says that after the swelling goes down and the ear heals, Walters will have an ear that both looks and functions normally."

ananyo writes "Two species of African spiny mouse have been caught at something no other mammal is known to do — completely regenerating damaged tissue. The work could help improve wound healing in humans. The species — Acomys kempi and Acomys percivali — have skin that is brittle and easily torn, which helps them to escape predators by jettisoning patches of their skin when caught or bitten. Researchers report that whereas normal laboratory mice (Mus musculus) grow scar tissue when their skin is removed, African spiny mice can regrow complete suites of hair follicles, skin, sweat glands, fur and even cartilage (abstract). Tissue regeneration has not been seen in mammals before, though it is common in crustaceans, insects, reptiles and amphibians."

fangmcgee writes "Lab-grown leather apparel could hit the runways in as little as five years—all without harming a hair on a single animal's head, according to Andras Forgacs, co-founder and CEO of Modern Meadow, a Missouri-based startup that's approaching meat-and-leather production from a tissue-bioengineering, rather than farming, point of view. Backed by Breakout Labs, the grant-awarding foundation headed by PayPal co-founder Peter Thiel, Modern Meadow seeks to combine regenerative medicine with three-dimensional printing to synthesize leather and ultimately meat."

When you think of garage-based tech start-ups, hardware makers like Apple or data-manipulators like Google probably spring to mind before biotech, and way before farming. Lewis Weil, though, has for the last several years been perfecting the art of growing seaweed in central Texas, and his Austin Sea Veggies have garnered interest from gourmets and restaurants across the U.S. In large part, that's because seaweed is so useful for industrial purposes, it's getting harder to find eating seaweed these days. Lewis says there's nothing stopping anyone with an interest in aquaculture in emulating his success as an inland ocean farmer, but has some cautions, too -- when small things go wrong, or a record heatwave overcomes humans' puny air conditioning systems, your seaweed harvest can fail just like any other crop. Update: 09/19 16:40 GMT by T : Now with transcript! If video's too slow and linear, click below to read what Lewis had to say.

puddingebola sends this excerpt from an article at ScienceNow: "Scientists have enabled deaf gerbils to hear again — with the help of transplanted cells that develop into nerves that can transmit auditory information from the ears to the brain. The advance, reported today in Nature, could be the basis for a therapy to treat various kinds of hearing loss. ... Rivolta and his colleagues knew that during embryonic development, a handful of proteins, including fibroblast growth factor (FGF) 3 and 10, are required for ears to form. So they exposed human embryonic stem cells to FGF3 and FGF10. Multiple types of cells formed, including precursor inner-ear hair cells, but they were also able to identify and isolate the cells beginning to differentiate into the desired spiral ganglion neurons. Then, they implanted the neuron precursor cells into the ears of gerbils with damaged ear neurons and followed the animals for 10 weeks. The function of the neurons was restored.'"

Mansing writes "Citizens need to evaluate if they are indeed safer for all the 'security precautions' put into place. 'The U.S. Department of Homeland Security has rushed to acquire a new, multibillion-dollar version of the BioWatch system for detecting biological attacks without establishing whether it was needed or would work, according to a new report by a nonpartisan investigative arm of Congress. ... The existing system's repeated false alarms have triggered tense, high-stakes deliberations over whether to order mass evacuations, distribute emergency medicines or shut down major venues.' Is this just more money funneled to U.S. companies, or is this really keeping the U.S. safer? Are the same types of 'security precautions' being instituted in Spain and the UK? Or is this preying on fear a uniquely U.S. phenomenon?"

ananyo writes "In what is likely to be a historic moment in science, ENCODE, the Encyclopedia of DNA Elements, has published 30 papers in Nature, Genome Research and Genome Biology today, assigning some sort of function to roughly 80% of the genome, including more than 70,000 'promoter' regions — the sites, just upstream of genes, where proteins bind to control gene expression — and nearly 400,000 'enhancer' regions that regulate expression of distant genes. The project was designed to pick up where the Human Genome Project left off. Although that massive effort revealed the blueprint of human biology, it quickly became clear that the instruction manual for reading the blueprint was sketchy at best. Researchers could identify in its 3 billion letters many of the regions that code for proteins, but those make up little more than 1% of the genome, contained in around 20,000 genes. ENCODE, which started in 2003, aims to catalog the 'functional' DNA sequences between genes, learn when and in which cells they are active and trace their effects on how the genome is packaged, regulated and read. Nature has set up an ENCODE site with an explorer, that groups the papers by topic, and collects all the papers, which are available free."

Zothecula writes "The Forest Products Laboratory of the US Forest Service has opened a US$1.7 million pilot plant for the production of cellulose nanocrystals (CNC) from wood by-products materials such as wood chips and sawdust. Prepared properly, CNCs are stronger and stiffer than Kevlar or carbon fibers, so that putting CNC into composite materials results in high strength, low weight products. In addition, the cost of CNCs is less than ten percent of the cost of Kevlar fiber or carbon fiber. These qualities have attracted the interest of the military for use in lightweight armor and ballistic glass (CNCs are transparent), as well as companies in the automotive, aerospace, electronics, consumer products, and medical industries."

submeta writes "Researchers at MIT and the University of Pennsylvania have genetically engineered skeletal muscle cells to respond to light. The hope is that this 'bio-integrated' approach may lead to 'highly articulated, flexible robots.' The technique, known as optogenetics, has previously been used to stimulate neurons in worms to fire."

ananyo writes "Tens of thousands of years ago modern humans crossed paths with the group of hominins known as the Neandertals. Researchers now think they also met another, less-known group called the Denisovans. The only trace that we have found, however, is a single finger bone and two teeth, but those fragments have been enough to cradle wisps of Denisovan DNA across thousands of years inside a Siberian cave. Now a team of scientists has been able to reconstruct their entire genome from these meager fragments. The analysis supports the idea that Neandertals and Denisovans were more closely related to one another than either was to modern humans and also suggests new ways that early humans may have spread across the globe." wombatmobile linked to an article that focuses on the new techniques used to sequence the DNA of the bone fragments in question.